Common Coriolus Mushroom vs. Cancer
Known in English as Turkey Tail, Coriolus versicolor is a contender for the title "World's Most Common Mushroom." You can find it from tropical rain forests to the Siberian taiga, feasting on dead wood.
So considering these vastly different environments and all the other fungi and bacteria it has to compete with for survival, it's a qualified guess the Coriolus has a strong immune system, with an array of potential medicinal compounds.
In traditional Chinese medicine, Coriolus versicolor extract is used to treat liver cancer and some types of jaundice. [160] In modern medicine, the best known and most researched medicinal extract of Turkey Tail Mushroom is called PSK. It is used in Asia as an anti-cancer drug under the brand name Krestin. [188]
Two Japanese studies in the 1990's encompassing a total of 486 patients showed an increased survival rate from gastric cancer when PSK was added to conventional chemotherapy treatment. [161, 162, 163] It's also been found that PSK reduces cancer metastasis and recurrence. [161, 162, 164]
Two other polysaccharides from Coriolus versicolor extract have been found to have an inhibitory effect on leukemia. The polysaccharide CVP was shown to inhibit leukemia cell proliferation without any negative effect on normal lymphocytes. [165, 166, 167] Another smaller polysaccharide named SPCV also had an inhibitory effect on leukemia cells. [168]
Coriolus versicolor extract appears to combat cancer in two ways:
1) By directly inhibiting cancer cell growth and proliferation.
2) By enhancing Natural Killer (NK) cell activity. [169, 170, 171] Natural killer cells are a critical part of the human immune system's fight against cancer.
PSK is used in Asia to treat cervical cancer in conjunction with standard radiation therapy, through which it has been shown to increase survival rate. [134] In a 2001 U.S. study at the New York Medical College, it was also shown to decrease tumor growth in hormone responsive prostate cancer. [172]
Other cancer types where PSK shows promising results include lung, breast and colon cancer, [25, 173] but not Sarcoma 180. [174]
PSK has also been proven as a potent antibiotic, in particular against strains of Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Cryptococcus neoformans, Escherichia coli and Listeria monocytogenes. [175, 176, 177, 178, 179]
Tests in vitro (test tubes / Petri dishes - not live subjects) have even shown a compound (PSP) from Coriolus versicolor extract to inhibit the replication [180] and infection of HIV. [181]
In 1995, a study on rheumatoid arthritis and PSK reported normalization of immune function. [182]
In the book Growing Gourmet and Medicinal Mushrooms, Paul Stamets mentions being aware of several individuals with Hepatitis C reporting relief of symptoms from using medicinal mushroom tea. He specifically relates a case of a man with swollen liver and spleen starting on a daily regimen of tea made from Coriolus versicolor (Turkey Tail Mushroom) and Ganoderma lucidum (Reishi). After two weeks, the swelling went down and liver enzymes normalized. His HCV value went from 1.3 million to 140,000. [183]
Coriolus versicolor extracts also contain many antioxidant compounds, [184, 185, 186, 187] and may assist the recovery of the spleen after radiation. [189]
Finally, in the book Mycelium Running, Paul Stamets lists two additional areas of promising research on Coriolus versicolor: Kidney health and uterine cancer. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Always consult a licensed medical practitioner before using any herb (or mushroom) for medicinal purposes.
Credit: Thank you to Paul Stamets for source material. - 17269
So considering these vastly different environments and all the other fungi and bacteria it has to compete with for survival, it's a qualified guess the Coriolus has a strong immune system, with an array of potential medicinal compounds.
In traditional Chinese medicine, Coriolus versicolor extract is used to treat liver cancer and some types of jaundice. [160] In modern medicine, the best known and most researched medicinal extract of Turkey Tail Mushroom is called PSK. It is used in Asia as an anti-cancer drug under the brand name Krestin. [188]
Two Japanese studies in the 1990's encompassing a total of 486 patients showed an increased survival rate from gastric cancer when PSK was added to conventional chemotherapy treatment. [161, 162, 163] It's also been found that PSK reduces cancer metastasis and recurrence. [161, 162, 164]
Two other polysaccharides from Coriolus versicolor extract have been found to have an inhibitory effect on leukemia. The polysaccharide CVP was shown to inhibit leukemia cell proliferation without any negative effect on normal lymphocytes. [165, 166, 167] Another smaller polysaccharide named SPCV also had an inhibitory effect on leukemia cells. [168]
Coriolus versicolor extract appears to combat cancer in two ways:
1) By directly inhibiting cancer cell growth and proliferation.
2) By enhancing Natural Killer (NK) cell activity. [169, 170, 171] Natural killer cells are a critical part of the human immune system's fight against cancer.
PSK is used in Asia to treat cervical cancer in conjunction with standard radiation therapy, through which it has been shown to increase survival rate. [134] In a 2001 U.S. study at the New York Medical College, it was also shown to decrease tumor growth in hormone responsive prostate cancer. [172]
Other cancer types where PSK shows promising results include lung, breast and colon cancer, [25, 173] but not Sarcoma 180. [174]
PSK has also been proven as a potent antibiotic, in particular against strains of Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Cryptococcus neoformans, Escherichia coli and Listeria monocytogenes. [175, 176, 177, 178, 179]
Tests in vitro (test tubes / Petri dishes - not live subjects) have even shown a compound (PSP) from Coriolus versicolor extract to inhibit the replication [180] and infection of HIV. [181]
In 1995, a study on rheumatoid arthritis and PSK reported normalization of immune function. [182]
In the book Growing Gourmet and Medicinal Mushrooms, Paul Stamets mentions being aware of several individuals with Hepatitis C reporting relief of symptoms from using medicinal mushroom tea. He specifically relates a case of a man with swollen liver and spleen starting on a daily regimen of tea made from Coriolus versicolor (Turkey Tail Mushroom) and Ganoderma lucidum (Reishi). After two weeks, the swelling went down and liver enzymes normalized. His HCV value went from 1.3 million to 140,000. [183]
Coriolus versicolor extracts also contain many antioxidant compounds, [184, 185, 186, 187] and may assist the recovery of the spleen after radiation. [189]
Finally, in the book Mycelium Running, Paul Stamets lists two additional areas of promising research on Coriolus versicolor: Kidney health and uterine cancer. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Always consult a licensed medical practitioner before using any herb (or mushroom) for medicinal purposes.
Credit: Thank you to Paul Stamets for source material. - 17269
About the Author:
Dr. Markho Rafael currently specializes in researching and writing about medicinal mushrooms in cooperation with Cordyceps Reishi Extracts, LLC, an NC company offering Coriolus extract (Stamets') and other medicinal mushrooms. For article references, please go to Coriolus versicolor extract (Stamets') and click on any number indicating a reference.
posted by X - Men at
7:35 AM
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